Table E5.
Coronavirus disease 2019–related outcomes results of patients with different blood AEC categories compared with patients with eosinopenia defined by AEC less than 0.1 × 103 cell/μLE12
| All patients | n | Hospitalization |
Intensive care unit admission |
Hospital mortality |
|---|---|---|---|---|
| OR (95% CI) | OR (95% CI) | OR (95% CI) | ||
| AEC (×103 cell/μL) | ||||
| <0.1∗ | 15,512 | 1 | 1 | 1 |
| 0.1-0.2 | 18,250 | 0.74 (0.70-0.79) | 0.83 (0.73-0.92) | 0.66 (0.58-0.77) |
| 0.2-0.3 | 6,933 | 0.79 (0.73-0.86) | 0.89 (0.77-1.02) | 0.77 (0.65-0.91) |
| >0.3 | 5,702 | 0.88 (0.81-0.96) | 0.91 (0.79-1.05) | 0.84 (0.71-0.99) |
| No inhaled corticosteroids | ||||
| <0.1∗ | 14,088 | 1 | 1 | 1 |
| 0.1-0.2 | 16,468 | 0.75 (0.71-0.81) | 0.84 (0.74-0.95) | 0.68 (0.58-0.79) |
| 0.2-0.3 | 6,082 | 0.82 (0.75-0.89) | 0.96 (0.82-1.12) | 0.80 (0.66-0.97) |
| >0.3 | 4,748 | 0.94 (0.86-1.03) | 0.95 (0.81-1.12) | 0.95 (0.79-1.16) |
| Inhaled corticosteroids | ||||
| <0.1∗ | 1,424 | 1 | 1 | 1 |
| 0.1-0.2 | 1,782 | 0.68 (0.58-0.81) | 0.74 (0.58-0.95) | 0.61 (0.44-0.83) |
| 0.2-0.3 | 851 | 0.65 (0.53-0.79) | 0.63 (0.46-0.86) | 0.67 (0.46-0.96) |
| >0.3 | 954 | 0.64 (0.53-0.79) | 0.75 (0.56-1.01) | 0.52 (35-76) |
AEC, absolute eosinophil count; CI, confidence interval; OR, odds ratio.
The analysis was adjusted for demographics, baseline AEC, month of testing, smoking status, pack-years smoking, medications, and comorbidities.
∗
Patients with preexisting AEC measurements were stratified into four categories. Those with an AEC greater than 0.3, 0.2 to 03, and 0.1 to 0.2 were compared with patients with eosinopenia (defined by an AEC less than 0.1 × 103 cell/μL).