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. 2021 Aug 13;15(1):60–69. doi: 10.1093/ckj/sfab149

Table 6.

Salient characteristics of major CKD cohort studies in adult population

Characteristic ICKD (n = 4056) CRIC [5, 18] (n = 3612) CKD-JAC [6] (n = 2977) GCKD [19] (n = 5217) CanPREDDICT [7] (n = 2402) C-STRIDE [11] (n = 3168) KNOW-CKD [10] (n = 2238) NEFRONA [8]
Age (years), mean ± SD 50.3 ± 11.8 58.2 ± 11.0 60.8 ± 11.6 60.1 ± 12.0 68.1 ± 12.7 48.2 ± 13.7 53.7 ± 12.2 57.9 ± 12.8
Female sex, % 32.8 46.0 38.0 40.0 37.0 41.0 38.8 42.3
BMI, kg/m2, mean ± SD 24.4 ± 5.8 32.1 ± 7.9 23.5 ± 3.8 29.8 ± 6.0 24.5 ± 3.6 24.6 ± 3.4 28.3 ± 5.2
eGFR, mL/ min/ 1.73 m2, mean ± SD 40.6 ± 17.2 43.4 ± 13.5 28.6 ± 11.8 47.0 ± 17.0 28.0 ± 9.0 50.7 ± 30.0 53.1 ± 30.7 CKD Stage 3–5D
Diabetes, % 37.5 47.0 37.6 35.3 48.0 22.8 33.7 25.7
Hypertension, % 87.0 86.0 81.5 95.0 Not available 77.8 96.1 89.3
CVD, % 21.8 33.0 25.6 32.2 22.0 9.8 6.0 NA
Tobacco use, % 18.6 14.0 16.4 14.9 Not available 38.2 15.7 19.4
Major cause of CKD

  • DKD (24.9)

  • CGN (14.7)

  • HTN (7.9)

  • CIN (23.2)

  • Unknown (19.4)

  • DKD (25.5)

  • HTN (14.5)

  • Other (13.7)

  • Do not know (46.3)

  • DKD (20.6)

  • CGN (31.9)

  • Others (47.5)

  • DKD (15.0)

  • CGN (19.0)

  • Vascular nephropathy (23.0)

  • Interstitial nephropathy (4.6)

  • Unknown [20]

  • DKD (29.0)

  • CGN (11.0)

  • HTN (27.0)

  • PKD (4.0)

  • Others (29.0)

  • DKD (13.9)

  • CGN (60.6)

  • Others (25.6)

  • DKD (23.2)

  • CGN (36.2)

  • HTN (18.3)

  • PKD (16.3)

  • Unknown (6.1)

  • DKD (14.4)

  • CGN (15.6)

  • Vascular nephropathy (19.3)

  • tubulointerstitial (11.7)

  • Unknown (16.7)