Table 1.
Score | Variables | Significance | Severity cutoff | Mortality observed | ||
Maddrey’s DF | Bilirubin, PT | Evaluates risk of mortality at 30 days | <32: non-severe | ≥32: severe |
At 30 days:
• DF <32: < 10% • DF ≥32: > 20–30% |
|
MELD | Bilirubin, INR, creatinin | Evaluates risk of mortality at 90 days | <21: non-severe | ≥21: severe |
At 90 days:
• MELD <21: <20% • MELD ≥21: ≥20% The probability of 90-day mortality according to MELD score can be calculated with the next formula: P = e(−4.3+0.16 × MELD) / [1+e(−4.3+0.16 × MELD)]) |
|
GAHS | Bilirubin, INR, urea, WBC, age | Evaluates risk of mortality at 28 days and 84 days | <9: nonsevere | ≥9: severe |
At 28 days:
• GAHS <9: 13% • GAHS ≥9: 54% At 84 days: • GAHS <9: 21% • GAHS ≥9: 60% |
|
ABIC | Bilirubin, INR, creatinin, age | Evaluates risk of mortality at 90 days and 1 year | <6.71: low risk | 6.71–8.99: intermediate risk | ≥9: high risk |
At 90 days:
• ABIC <6.71: 0% • ABIC 6.71–8.99: 30% • ABIC ≥9: 75% At 1 year: • ABIC <6.71: 2.9% • ABIC 6.71–8.99: 35.7% • ABIC ≥9: 66.7% |
Abbreviations: ABIC, Age, serum Bilirubin, INR, and serum Creatinine; DF, Discriminant Function; GAHS, Glasgow Alcoholic Hepatitis Score; INR, International Normalized Ratio; MELD, Model for End-Stage Liver Disease; PT, prothrombin time; WBC, white blood cell count