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CT, SWI, and T2-weighted images of a boy with a TREX1 mutation. The upper row shows imaging at 2 months of age, and the lower row, at 2 years of age. There are periventricular, basal ganglia, brainstem, and cerebellar WM calcifications, which progress with time. Note the interval volume loss with WM rarefaction, most marked in the anterior temporal lobes.
