Figure 1. Wuhan-hu-1, PMS20, and Omicron Plasma Neutralizing Titers.

Panel A shows the trajectories of NT₅₀ values against Wuhan-hu-1, polymutant spike protein (PMS20), and omicron pseudotypes in previously unvaccinated persons who had recovered from Covid-19, measured approximately 1 month (mean ±SD, 41±12 days) and 6 months (194±12 days) after infection and then at approximately 1 year (360±15 days) after infection, which corresponded to 41±21 days after vaccination (“plus vaccine”) (see Table S2). Panel B shows the trajectories of NT₅₀ values against Wuhan-hu-1, PMS20, and omicron pseudotypes in persons who had received an mRNA vaccine, measured 1 month (42±19 days) and 5 months (165±33 days) after the second dose of an mRNA vaccine and at 30±18 days after the third dose (“boost”) that was administered at least 6 months after the second dose.