. 2022 Jan 10;37(1):451–461. doi: 10.1080/14756366.2021.2018682

Table 1.

Inhibition of all the synthesised OA derivatives against α-glucosidase and α-amylase. Inline graphic

Compounds	α-Glucosidase inhibition (IC₅₀:μM)	α-Amylase inhibition (IC₅₀:μM)
3a	0.35 ± 0.06^a	7.86 ± 1.24^a
3b	0.68 ± 0.03^a	15.26 ± 1.41^a
3c	0.89 ± 0.07^a	25.37 ± 1.17^a
3d	1.45 ± 0.12^a	17.47 ± 1.52^a
3e	0.95 ± 0.06^a	5.64 ± 1.29^a
3f	1.28 ± 0.03^a	3.80 ± 0.65^a
3g	3.13 ± 0.13^a	12.57 ± 2.37^a
3h	1.36 ± 0.03^a	18.29 ± 1.92^a
3i	0.71 ± 0.02^a	17.87 ± 1.21^a
3j	0.82 ± 0.09^a	70.81 ± 2.31^a
3k	0.67 ± 0.04^a	25.57 ± 1.66^a
3l	0.99 ± 0.05^a	55.30 ± 2.39^a
3m	1.10 ± 0.10^a	35.47 ± 2.41^a
3n	1.96 ± 0.25^a	70.21 ± 2.53^a
3o	1.74 ± 0.14^a	26.32 ± 1.61^a
3p	1.81 ± 0.05^a	15.93 ± 1.75^a
3q	3.43 ± 0.17 ^a	33.61 ± 1.93^a
3r	1.41 ± 0.12^a	70.72 ± 1.25^a
3s	1.37 ± 0.06^a	18.68 ± 1.29^a
3t	0.91 ± 0.04^a	152.36 ± 4.24^a
OA	4.09 ± 0.11^b	94.10 ± 1.72^b
Acarbose	665.56 ± 13.92^c	100.01 ± 2.73^c

Values are the mean ± SD. Mean values in the same column having different letters are significantly different (p < 0.05).