Figure 4.

Matrix factorization used to identify two biologic programs which determine outcome in older and hyperinflamed patients. For older patients and hyperinflamed patients, optimal treatment consists of very early anti-IL6 therapy (<4^th day) or delayed (day 7^th-9^th) dexamethasone therapy. Matrix factorizations divides the patient-feature matrix into patient-program and program-feature matrices. The plot here depicts the feature contribution to 2 clinical programs that were generated during factorization.