Table 4.

Study characteristics related to orthodontic therapy.

Authors (year)	Type of malocclusion	Type of OT	Total duration of OT	Oral complications	Treatment of oral complications	Outcome of OT
Jaffa (2007) [24]	NR	Fixed appliances	NR***	Sore mouth	NR	NR
	NR	Fixed appliances	NR***	Sore mouth	NR	NR
Lee et al. (2015) [13]	NR	Fixed appliances	NR****	Sore mouth	NR	NR
	NR	Fixed appliances	NR****	Recurrent oral ulcers, sore mouth	NR	NR
Corega et al. (2014) [6]	Crowding	Fixed appliances	10 months	Generalized gingivitis and denineralizations, WSLs, diffuse erythema	Referral to dentist for restorative treatment	OT was discontinued
	Class II Division 2	Fixed appliances combined with planned orthognathic surgery*	7 months	Generalized gingivitis and denineralizations, WSLs	Referral to dentist for restorative treatment	OT was discontinued
Shaw (1994) [15]**	Class I, anterior closed bite, mandibular anterior crowding, narrow arches	Removable maxillary bite plane with expansion screws, stripping and fixed appliances	~8 months**	Incisal-lingual enamel erosions of upper incisors, canines and premolars, and lower incisor over-eruption	OT to increase interincisal space followed by placement of porcelain veneer crowns on upper incisors	Successful

OT, orthodontic treatment; NR, not reported; WSLs, white spot lesions.

^*The OT was discontinued at the final presurgical phase.

^**The patient also had a prior history of OT when she was 9–11 years old.

^***The author reported time of hospitalization after 2 years of OT.

^****The authors reported time of hospitalization after 23 months of OT for the first case and after 7 months for the second.