Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jan 5;3:772275. doi: 10.3389/fmedt.2021.772275

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Rojas-Jiménez, Solano, Segura, Sánchez, Chaves-Araya, Herrera, Vargas, Cerdas, Calvo, Alfaro, Molina, Bolaños, Moreira-Soto, Villalta, Sánchez, Cordero, Durán, Solano, Gómez, Hernández, Sánchez, Vargas, Drexler, Alape-Girón, Díaz and León.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Production of VP-IVIg and CP-IVIg by the method of caprylic acid precipitation: (A) Collection, testing and approval of raw plasma. (B) Precipitation of plasma proteins by addition of caprylic acid 5–6% (v/v). (C) Removal of precipitates by gravity filtration. (D) Diafiltration, concentration and formulation. (E) Strong anion exchanger chromatography. (F) Readjustment of the formula. (G) Sterilizing filtration. (H) Filling in type 1 borosilicate vials (40 mL/vial). (I) Lyophilization.