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. 2021 Jun 30;3:694347. doi: 10.3389/fmedt.2021.694347

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Copyright © 2021 Giron, Laaksonen and Barroso da Silva.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Graphical Abstract — Effects of the conformational states of the SARS-CoV-2 spike protein variants on their electrostatic stability and their impact on virulence.