Table 1.
Summary of highlighted in vitro studies on immune cell transendothelial migration.
| References | Endothelium | Migratory cell line | Extracellular matrix | Inflammatory stimulus | Flow |
|---|---|---|---|---|---|
| Allingham et al. (9) | Human umbilical vein | HL-60 & primary human neutrophils | Matrigel | 10 ng/mL TNF-α | |
| Bixel et al. (10) | Mouse bend.5 | Mouse neutrophils | Laminin | 5 nM TNF-α or 10 ng/mL IL-1β | |
| Buffone et al. (11) | Human umbilical vein | HL-60 & primary human neutrophils | IL-1β | 100 to 800 s−1 | |
| Carman et al. (12) | Human umbilical vein | Primary human neutrophils, monocytes, & lymphocytes | Fibronectin | 100 ng/mL TNF-α | |
| Green et al. (13) | Transfected L-cells, CHO, or human umbilical vein | Primary human neutrophils | 200 U/mL TNF-α | 1 dyn/cm2 | |
| Khire et al. (14) | Human umbilical vein | Primary human neutrophils | Collagen I gel & fibronectin | 10 dyn/cm2 | |
| Mossu et al. (15) | Human brain like | T cells | Gelatin | 10 ng/mL TNF-α | 0.1–1.5 dyn/cm2 |
| O'Brien et al. (16) | REN mesothelioma | Primary human neutrophils | Fibronectin | 10 U/mL IL-1β or 100 U/mL TNF-α | |
| Salminen et al. (17) | Human umbilical vein | Primary human neutrophils | Collagen I gel or fibronectin | 4.5 dyn/cm2 | |
| Shaw et al. (18) | Human umbilical vein | Primary human neutrophils | Fibronectin | 25 ng/mL TNF-α | 1 dyn/cm2 |
| Steiner et al. (19) | Primary mouse brain microvessel | T cell line SJL.PLP7 | Matrigel | 25 ng/mL TNF-α | 0.25–1.5 dyn/cm2 |
| Watson et al. (20) | Human umbilical vein or mouse heart | Human mononuclear leukocytes & neutrophils or mouse leukocytes | Collagen I gel | TNF-α or IL-1β | |
| Yang et al. (21) | Human umbilical vein | Primary human neutrophils & T cells | Fibronectin | 25 ng/mL TNF-α | 1 dyn/cm2 |