Table 3.

Risk factors considered associated with the survival in 570 COVID-19-positive patients

	Univariate model		Multivariate model*
Risk factor	Hazard ratio (95% CI)	p value	Hazard ratio (95% CI)	p value
Age#	1.06 (1.04–1.07)	< 0.0001
median value	Reference		Reference
median value	4.99 (2.99–8.33)	< 0.0001	4.28 (2.55–7.19)	< 0.0001
Sex
Female	Reference
Male	1.05 (0.71–1.57)	0.8
VRS†	1.17 (1.11–1.24)	< 0.0001	1.13 (1.07–1.94)	< 0.0001
ILD†	1.02 (1.017–1.03)	< 0.0001
TSS†	1.11 (1.07–1.16)	< 0.0001

^# Median age in the 570 COVID-19-positive patients: 66 years

^* Model selection: best Bayesian information criterion (BIC)

^† VRS (pulmonary vascular-related structures percentage) is defined as the ratio between the total vessel

volume and the total lung parenchymal volume

ILD interstitial lung disease extent %; TSS total severity score