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. 2022 Jan 13;17(1):e0262454. doi: 10.1371/journal.pone.0262454

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© 2022 Lungu et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — (a) Shows comparison of IL-6 in fresh whole blood pre and post-stimulation. IL-6 increased significantly post-stimulation, 1,741 (91.5–6829 pg/ml) in pre-stimulation to 6,215 (4,180–14,380 pg/ml) post stimulation p value = 0.0039. (b) Shows the comparison of IFNγ in pre and post stimulation. IFNγ increased significantly post stimulation, P value = 0.0176. (c) Shows a comparison of TNF-α pre and post-stimulation. There is a notable increase in TNF-α post stimulation. 28.8 (0.0–244 pg/ml) in pre-stimulation vs 170.3 (26.1–268.5 pg/ml) in post stimulation, p value = 0.2462. (d) Shows the change in expression of IL-10 post stimulation. It compares pre and post-stimulation levels of IL-10. No significant difference in expression of IL-10 between pre and post stimulation. 11.38 (0.0–33.27 pg/ml) in pre-stimulation 21.9 (10.88–52.59 pg/ml) in post stimulation in, p value = 0.0898.