Table 1. Social-economic and clinical characteristics of tuberculosis patients.
Variable | HIV Positive (n = 39) | HIV negative (n = 31) | P-Value |
---|---|---|---|
Sex | |||
Male | 23(59.0%) | 28(90.3%) | 0.002* |
Female | 16(41.0%) | 3(9.7%) | |
Age Median (IQR) | 35(28–42) | 31(25–36) | 0.096 |
Residence | |||
High Density | 25(64.1%) | 25(80.6%) | 0.165 |
Low Density | 14(35.9) | 6(19.4) | |
Site of TB Infection | |||
Pulmonary | 38(97.4%) | 30(97.0%) | 0.68 |
Extra-pulmonary | 1(2.6%) | 1(3.0%) | |
Episodes of TB | |||
1st | 28(71.8%) | 23(73.2%) | 0.948 |
2nd | 10(25.6%) | 7(22.6%) | |
3rd | 1(2.6%) | 1(3.2%) | |
BMI (Median, IQR) | 20.5(17.9–23.4) | 20.3(18.5–21.2) | 0.240 |
Karnofsky score | |||
Fifty | 3(7.7%) | 0(0%) | 0.328 |
Sixty | 1(2.6%) | 1(3.2%) | |
Seventy | 3(7.7%) | 3(9.7%) | |
Eighty | 32(82.0%) | 26(83.9%) | |
Ninety | 0(0%) | 1(3.2%) | |
CD4 count (Cells/mm 3 ) | 345 (157–483) | 563 (465–702.5) | <0.001* |
CD4 count categories | |||
≤ 200 | 12(30.86%) | 1(3.2) | 0.004* |
201–499 | 19(48.7%) | 10(32.3%) | |
≥ 500 | 8(20.5%) | 20(64.5%) |
*Statistically significant.
Table 1 shows the demographics and characteristics of patients with active TB distinguished by the HIV serostatus. 39 were HIV positive and 31 were HIV negative. There were more males than females, 23 (59.0%) and 28 (90.3%) were males in the HIV positive and HIV negative groups respectively p value = 0.002. There was no difference in the age distribution, residence, site of infection, bacterial load, episodes of TB, BMI and functional status (karnofsky score). The two groups were significantly different in the distribution of CD4 count. Median (IQR) 563 (465–702.5 cells/mm3) vs 345 (157–483 cell/mm3) in HIV negative vs HIV positive respectively p value = <0.001.