Table 4. Adverse events.
Patient | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | |
Hematologic events | |||||||||
Thrombocytopenia (gr) | 4 | 3 | 1 | 3 | 2 | 3 | 4a | 4 | |
Leukopenia (gr) | 4 | 4 | 4 | 4 | 1 | 4 | 4 | 4 | |
Anemia (gr) | 3 | 2 | 2 | 2 | 2 | 2 | 3b | 3b | |
Lymphopenia (gr) | 3 | 3 | 3 | 4 | 3 | 4 | 3 | 3 | |
Neutropenia (gr) | 4 | 4 | 4 | n/a | - | 4 | n/a | n/a | |
Non-hematologic events | |||||||||
Elevated AST (gr) | 2 | 2 | 1 | 3 | 3 | 1 | 2 | - | |
Elevated ALT (gr) | 1 | 1 | - | n/a | n/a | 2 | - | - | |
Elevated bilirubin (gr) | 2 | - | - | n/a | n/a | 2 | - | - | |
Fever, treatment related (gr) | 2 | 1 | - | - | 1 | 1 | - | - | |
Nausea (gr) | - | 1 | 2 | - | 1 | 1 | 2 | - | |
Alopecia (gr) | 1 | - | - | - | - | - | - | 1 | |
Other | c | - | d | - | e | - | - | f |
Note: All patients received a subcutaneous injection of granulocyte-colony stimulating factor within 72h after each M-PHP procedure.
AST, aspartate transaminase; ALT, alanine transaminase; Bili, bilirubin; Gr, grade; n/a, not available; -, no adverse event.
a Treated with platelet transfusion.
b Treated with red blood cell transfusion.
c Haemorrhage groin, treated with a tight pressure dressing.
d Peripheral edema due to periprocedural overhydration, treated with diuretics.
e Lower urinary tract infection, treated with oral antibiotics.
f Aneurysma spurium, successfully treated with a thrombin injection.