Table 2.
Birth outcomes of people with SARS-CoV-2 infection during their first, second, or third trimester
|
First trimester (n=85) |
Second trimester (n=226) |
Third trimester (n=571) |
Total (n=882) |
Matched negative control (n=889) |
|||||
|---|---|---|---|---|---|---|---|---|---|
| N or median | p value | N or median | p value | N or median | p value | N or median | p value | N or median | |
| Stillbirth* | 1 (1·2%) | 0·05 | 5 (2·2%) | 0·06 | 1 (0·2%) | 0·36 | 7 (0·8%) | <0·05 | 1 (0·1%) |
| Small for gestational age*† | 9 (10·6%) | 0·79 | 29 (12·8%) | 0·37 | 78 (13·7%) | 0·08 | 117 (13·3%) | <0·05 | 91 (10·2%) |
| Fetal growth percentile‡ | 49 (49·2) | 0·29 | 47 (49·4) | 0·25 | 45 (48·6) | <0·05 | 46 (50·0) | <0·05 | 48 (51·0) |
| Gestational days‡ | 273 (13·0) | <0·05 | 273 (16·0) | <0·05 | 275 (13·0) | 0·38 | 274 (14·0) | 0·12 | 274 (12·0) |
| Birthweight, oz‡ | 117 (24·4) | <0·05 | 117 (23·9) | 0·07 | 118 (23·5) | <0·05 | 117 (23·7) | <0·01 | 119 (21·1) |
Data are n (%) or median (IQR), unless stated otherwise. Stillbirth and small for gestational age rates for people with maternal SARS-CoV-2 infections during their first, second, or third trimester compared with the matched negative control group. Median (IQR) of the fetal growth percentile at delivery, gestational age at delivery, and weight at delivery.
*
Categorical variables: Fisher's exact test.
†
Percentages reported are calculated from the total of infants whose birthweight at delivery was recorded.
‡
Continuous variables: Mann-Whitney U test.