Table 4.
Safety evaluation of LLLT and DSG/EE
| LLLT group (n = 72) | DSG/EE group (n = 63) | |||||
|---|---|---|---|---|---|---|
| Month 0 | Month 3 | p value | Month 0 | Month 3 | p value | |
| WBC, 109/L | 5.93 ± 0.24 | 5.60 ± 0.19 | 0.171 | 5.65 ± 0.21 | 5.68 ± 0.20 | 0.884 |
| HBG, g/L | 128.93 ± 1.29 | 127.84 ± 1.37 | 0.354 | 128.96 ± 1.45 | 129.71 ± 1.45 | 0.479 |
| PLT, 109/L | 245.87 ± 6.95 | 246.17 ± 6.61 | 0.949 | 242.95 ± 6.65 | 252.18 ± 6.74 | 0.018 |
| N, % | 58.07 ± 1.08 | 57.91 ± 1.06 | 0.899 | 57.91 ± 1.19 | 55.70 ± 1.24 | 0.093 |
| U-WBC | 0 ± 0 | 0 ± 0 | – | 0 ± 0 | 0 ± 0 | – |
| U-PRO | 0 ± 0 | 0 ± 0 | – | 0 ± 0 | 0 ± 0 | – |
| ALT, IU/L | 12.19 ± 0.62 | 11.49 ± 0.74 | 0.215 | 12.17 ± 0.79 | 13.17 ± 0.98 | 0.288 |
| AST, IU/L | 15.59 ± 0.40 | 16.58 ± 0.54 | 0.046 | 16.17 ± 0.57 | 16.83 ± 0.52 | 0.167 |
| Cr, µmol/L | 59.02 ± 1.18 | 56.18 ± 1.09 | < 0.001 | 59.31 ± 1.55 | 59.96 ± 1.75 | 0.564 |
| UA, µmol/L | 268.23 ± 6.34 | 268.84 ± 6.49 | 0.914 | 271.28 ± 9.23 | 260.36 ± 6.51 | 0.101 |
| BUN, mmol/L | 4.14 ± 0.11 | 4.10 ± 0.13 | 0.724 | 4.17 ± 0.20 | 4.21 ± 0.18 | 0.775 |
LLLT, low-level light therapy; DSG/EE, desogestrel and ethinyl estradiol; RBC, red blood cell; HB, haemoglobin; WBC, white blood cell; PLT, platelet; N, neutrophil; ALT, serum alanine aminotransferase; AST, serum aspartate aminotransferase; Cr, creatinine; UA, uric acid; BUN, urea nitrogen
Quantitative variables are described as mean ± SEM