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. 2022 Jan 6;2022:2454168. doi: 10.1155/2022/2454168

Table 2.

Expression analysis of different markers involved in homing and migration.

Marker UC-MSCs BM-MSCs AT-MSCs Ref.
Secreted factors
COX-2 [45]
bFGF (FGF-2) ↑↑ [45]
HGF ↑↑ ↓↓ [45, 105]
IGF-1 [54]
IL-1α ↑↑ ND [54]
IL-1𝛽 ↑↑ [54, 105, 106]
IL-6 [105]
[45]
IL-8 [105]
IL-1RA [105]
MCP-1 (CCL2) [45, 105]
[45]
MIP-1α (CCL3) + [107, 108]
MIP-1𝛽 (CCL4) + - - [105]
OPN [109]
PDGF-AA [105, 107]
PDGF-AB - [107, 110]
PDGF-BB - - [105]
PGE2 [106]
PlGF ↓↓ [105]
SDF-1 [111, 112]
SDF-1α [45]
TGF-𝛽1 [105]
TGF-𝛽2 [105]
VEGF-A [45]
VEGF-D [105, 107]
MMPs and TIMPS
MMP-1 ↑↑ [105]
MMP-2 [113]
MMP-3 [105]
MMP-7 - [105]
MMP-8 - - [105]
MMP-13 - - + [105]
TIMP-1 [113]
TIMP-2 [113]
Adhesion molecules and receptors
CCR2 [54]
CXCR4 [114]
Flt-1 (VEGFR1) ND [54]
ICAM-1 ↑↑ [45]
Integrin α4 ↑↑ - [54]
PDGF-Ra [107]
PDGF-Rb [107]
VCAM-1 [45]
Immunoregulatory molecules
B7-H3 (CD276) + + + [71]
CD200 ↓↓ [54, 115]
Galectin 1 [113]
HLA-ABC [54, 116]
HLA-DR [54, 116]
HLA-G [54, 116]
HLA-E [54, 117]
HLA-F - [54, 117]
IDO [45]
↑↑ ND [118]
IP-10 [105]
LIF [54, 113]
PD-L1 (B7-H1) + [54, 119]
PD-L2 (B7-DC/CD273) + [54, 119]
RANTES (CCL5) [105]
TLR-1 [106]
TLR-2 [106]
TLR-3 [106]
TLR-4 - [106]
TLR-5 [106]
TLR-6 [106]
TLR-9 [106]

Expression: ↑: higher; ↑↑: significantly higher; ↓: lower; ↓↓: significantly lower; ↔: similar; +: qualitatively expressed, but not quantified; -: not expressed; ND: not detected.