Table 2.
Semisynthetic of new bioactive compounds from E. officinarum latex.
| No. name | Tested activity | References |
|---|---|---|
| 18. 3β-Acetoxy-norlup-20-one (1) 19. 3-Chloro-4α,14α-dimethyl-5α-cholest-8-ene (2) |
Antibacterial activity | [10] |
| (i) Pseudomonas syringae pv. syringae (pss) | ||
| (ii) P. syringae pv. tabacci (pst) | ||
| (iii) Erwinia amylovora (Ea) | ||
| (iv) Agrobacterium tumefaciens (At) | ||
| Antifungal activity | ||
| (i) V. dahliae (SH, SE, SJ, SA, SB, and E4) | ||
| (ii) Penicillium expansum | ||
| (iii) Fusarium oxysporum fsp. melonis. V. dahliae | ||
| (iv) F. oxysporum | ||
|
| ||
| 20. 3b-Tosyloxy-4a,14a-dimethyl-5a-ergost-8-en-24-one (C36H54O4S) (1) |
Antifeedant activity
(i) Spodoptera littoralis (ii) Myzus persicae (iii) Rhopalosiphum padi |
[20] |
| 21. 4a,14a-dimethyl-5a-ergost-8-en-3,24-dione (C30H48O2) 6 | ||
| 22. 4a,14a-Dimethyl-5a-ergosta-8,24-dien-3-one(C30H48O) (7) | ||
| 23. 4a,14a-Dimethyl-5a-cholest-8-ene-3,11-dione-7-thiadiazoline (C34H51O4N3S) (9) | ||
| 24. 4a,14a-dimethyl-5acholest-8-ene-7,11-dione-3-thiadiazoline (C34H51O4N3S) (11) | ||
| 25. 4a,14a-Dimethyl-5a-cholest-8-ene-3,11-dione-7 thiosemicarbazone (C30H45O2N3S) (8) | ||
| 26. 4a,14a-Dimethyl-5a-cholesta-7,9-diene-3-thiosemicarbazone(C30H49N3S) (10) | ||
| 27. 3b-Tosyloxy-4a,14a-dimethyl-5a-cholest-8-ene(C36H56O3S) (3) | ||
| 28. 3b-Tosyloxy-4a,14a-dimethyl-5acholest-8-ene-7,11-dione (C36H52O5S( (4( | ||
| 29. 3b-Acetoxy-4a,14a-dimethyl-5a-cholest-8-ene-7,11-dione (C31H48O4) (5) | ||
|
| ||
| 30. 1 3β-Tosyloxy-4α,14α-dimethyl-5α-ergosta-8-en-24-one (C36H54O4S) | Leishmanicidal activity | [8] |
| 31. 2 31-Norlanostenol (C29H50O) | (i) L. infantum | |
| 32. 3 3β-Tosyloxy-4α,14α-dimethyl-5α-cholest-8-ene (C36H56O3S) | Trypanocidal activity | |
| 33. 4 3β-Tosyloxy-4α,14α-dimethyl-5α-cholest-8-ene-7,11-dione (C36H52O5S) | (i) T. cruzi | |
| 34. 5 3β-Acetoxy-4α,14α-dimethyl-5α-cholest-8-ene-7,11-dione (C31H48O4) | Cytotoxicity test | |
| 35. 6 4α,14α-Dimethyl-5α-ergosta-8-ene-3,24-dione (C30H48O2) | (i) Mammalian CHO cells | |
| 36. 7 4α,14α-Dimethyl-5α-ergosta-8,24-dien-3-one (C30H48O) | ||
| 37. 8 4α,14α-Dimethyl-5α-cholest-8-ene-3,7,11-trione-7-thiosemicarbazone (C30H43O2N3S) | ||
| 38. 9 4α,14α-Dimethyl-5α-cholest-8-ene-3,7,11-trione-7-thiadiazoline (C34H51O4N3S) | ||
| 39. 10 4α,14α-Dimethyl-5α-cholesta-7,9-dien-3-one thiosemicarbazone (C30H49N3S) | ||
| 40. 11 3β-Acetoxy-norlup-20-one (C31H50O3) | ||
| 41. 12 3β-Hydroxy-norlup-20-one (C29H48O2) | ||
| 42. 13 4α,14α-Dimethyl-5α-cholest-8-ene-3,7,11-trione-3-thiadiazoline (C34H51O4N3S) | ||
|
| ||
| 43. 8α,9α-Epoxy-4α,14α-dimethyl-5α-cholest-3β-ol 2 | Antifeedant activity | [7] |
| 44. 4α,14α-Dimethyle-5α-cholesta-7,9-dien-3β-ol (3) 3 | (i) Spodoptera littoralis | |
| 45. 3-Chloro-4α,14α-dimethyl-5α-cholest-8-en-7-one 4 | Antiparasitic activity | |
| 46. 4α,14α-Dimethyl-5α-cholestat-8-en-3-one (C29H48O) 5 | (i) Trypanosoma cruzi | |
| 47. 2-Carbomethoxy-4α,14α-dimethyl-5α-cholesta-2,8-dien-3-ol 6 | (ii) Leishmania infantum | |
| 48. 8α,9α-Epoxy-4α,14α-dimethyl-5α-cholest-3-one 7 | Cytotoxicity test | |
| 49. 4α,14α-Dimethyl-5α-cholest-8-ene-3,7-dione 8 | (i) Mammalian CHO cells | |
| 50. 4α,14α-Dimethyl-5α-cholest-8-en-3-one 9 | (ii) Insect Sf9 | |
| 51. 4α,14α-Dimethyl-7-oxo-5α-cholest-8-ene-3,4-lactone 10 | ||
| 52. 4α,14α-Dimethyl-7,11-dioxo-5α-cholest-8-ene-3,4-lactone 11 | ||
| 53. 8α,9α-Epoxy-4α,14α-dimethyl-5α-cholesta-3,4-lactone 12 | ||
| 54. 4α,14α-Dimethyl-5α-cholesta-7,9-diene-3,4-lactone 13 | ||
| 55. 4α,14α-Dimethyl-3,4-seco-5α-cholesta-7,9-diene-3,4-diol 14 | ||
| 56. 3-Carbomethoxy-4-hydroxy-4α,14α-dimethyl-3,4-seco-5α-cholesta-7,9-diene 15 | ||
| 57. 8α,9α,24,28-Diepoxy-4α,14α-dimethyl-5α-ergost-3β-ol 17 | ||
| 58. 8α,9α,24,28-Diepoxy-4α,14α-dimethyl-5α-ergosta-3,4-lactone 18 | ||
|
| ||
| 59. 3b-Tosyloxy-4a,14adimethyl- | Plant growth promoters activity | [21] |
| 5a-cholesta-7,9-diene F1 | ||
| 60. 4a,14a-dimethyl-5a-cholesta-7,9-dien-3b-ol F2 | ||
| 61. 3β-Acetoxynorlup- | [21] | |
| 20-one (F4) | ||
| 62. 3-Chloro-4α,14α-dimethyl-5α-cholest- | ||
| 8-ene (F6) | ||
|
| ||
| 63. 3β-Acetoxy-norlup-20-one | [21] | |
| 64. 3-Chloro-4α,14α-dimethyl-5α-cholest-8-ene | ||