Table 1.
Data collection process and data items: key details of the included studies: patient demographics and study specifications.
| Authors | Participant information | Demographics | Etiology/symptoms/referral source | Protocol | Participant positioning | Equipment | Frame rate | SIGN assessment of evidence a |
|---|---|---|---|---|---|---|---|---|
| Gullung et al. (2012) | 164 participants | Mean age 58 (range: 21–94), 75% female |
Primary complaint was dysphagia (59%), review included those ICD-9 codes for oral, oropharyngeal, and pharyngoesophageal types. Other diagnoses included choking sensation (15%), globus (11%), regurgitation or reflux (6%), aspiration pneumonia (4%), odynophagia (4%), and chronic cough (1%). | MBSImP protocol consisting of 11 swallows of various consistencies (Varibar). Esophageal clearance (Component 17) evaluated in the upright position with one 5-ml nectar-thick bolus and one 5-ml pudding bolus | Upright: lateral projection for imaging of oropharynx and in the A–P projection for imaging of the pharynx and esophagus | Not reported | Not reported | High quality |
| Madhavan et al. (2015) | 141 participants | Mean age 61.46 (range not reported), 37.59% female | All participants complained of globus sensation | Participants self-regulated bolus sizes of thin, nectar-thick, pudding Varibar, unmasticated marshmallow coated with contrast, and a 13-mm barium tablet | Lateral plane for the oropharyngeal imaging and the A–P plane for imaging of the esophagus in the standing position | Not reported | Not reported | Acceptable |
| Miles et al. (2015) | 111 participants | Mean age 71 (range: 20–95), 54% female |
36 participants with neurologic diagnoses, 37 participants with dysphagia of unknown cause, 28 participants with primary otolaryngology diagnosis, 10 participants in “other” (e.g., unwell elderly) category | 1 ml, 3 ml, and 20 ml of thin barium (EZ-Paque, EZ-EM), half a cup of thin barium via straw for oropharyngeal imaging. 20-ml bolus drunk consecutively and 13-mm barium tablet | Lateral plane for the oropharyngeal imaging and A–P projection while participant is upright, standing whenever possible for imaging of the esophagus | Videofluoroscope (Toshiba, Japan) and recorded on a USB drive with timing information was superimposed in 100ths of a second using a Horita VS-50 Video Stopwatch | 30 frames per second | High quality |
| Ortiz et al. (2019) | 216 participants | Mean age 63 (range not reported), 17% female | All participants reported globus pharyngeus sensation. Diagnosis reported for 99 participants: 6 neurodegenerative conditions, 22 with cancer history, 8 with Barrett's esophagus, 63 with extraesophageal reflux. Referral sources reported for 79 participants: 55 from gastroenterology, 24 from otolaryngology | Functional items assessed for oral, pharyngeal, pharyngoesophageal, and esophageal follow through listed. No materials were listed. | Not reported | Not reported | Not reported | Acceptable |
| Watts et al. (2019) | 307 participants | Mean age 60.5 (range: 15–95), 54% female | Referrals sources included: otolaryngology, pulmonology, neurology, gastroenterology, internal medicine, allergy, and rheumatology | Esophageal portion only: ¼ graham cracker with 5-cc barium paste (Varibar), a 13-mm barium tablet, two large swallows of barium (EZ-Paque; volume self-regulated) | Upright in the lateral and A–P projections for oropharyngeal imaging and in the A–P projection for esophageal imaging | Phillips BV Endura fluoroscopic C-arm unit (GE OEC 8800 Digital Mobile C-Arm system type 718074), recorded using the Digital Swallowing Workstation (Model 7120; Pentax) | 29.98 frames per second | High quality |
Note. MBSImP = Modified Barium Swallow Impairment Profile; Diagnostic code International Classification of Diseases, 9th version (ICD-9).
Scottish Intelligence Guidelines Network (2006) Methodology Checklist 5: Diagnostic Studies.