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. 2021 Dec 31;12:798652. doi: 10.3389/fendo.2021.798652

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Copyright © 2021 Chakraborty, Hegde, Praharaj, Prabhu, Patole, Shetty, Mayya, Acharya, Hande, Prabhu and Upadhya

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A detailed evaluation of the concentrations of individual species of monohexosylceramides (Hex 1 Cer, 22 species) in patients with MCI compared to the NC group of T2DM patients (A). This analysis identified significantly higher levels of Hex1Cer (d16:0_22:6) in patients with MCI compared to the NC group of T2DM patients [*p < 0.05, (A, B)]. Although variations were observed among several other Hex1Cer species, no significant differences were observed between the two groups.