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. 2021 Dec 31;12:798652. doi: 10.3389/fendo.2021.798652

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Copyright © 2021 Chakraborty, Hegde, Praharaj, Prabhu, Patole, Shetty, Mayya, Acharya, Hande, Prabhu and Upadhya

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A detailed evaluation of the individual species of sphingomyelins (SM), sphingosine (SPH), and phytosphingomelins (phSM) species in patients with MCI compared to the NC group of T2DM patients. Among 66 SM species evaluated in the targeted lipidomics, none of the species showed significant variations between the two studied groups (A). Similarly, analysis of 4 SPH species (B) and 2 phSM species (C) demonstrated no significant difference between the two groups.