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. 2021 Feb 26;36(2):1152–1163. doi: 10.1007/s00464-021-08382-5

Table 2.

Univariate and multivariate analysis of clinical factors associated with the success of FLNM

Univariate analysis Multivariate analysis
FLNM-f (n = 56) FLNM-s (n = 136) P value OR 95% C.I P value
Age (yr) 0.857
  < 70 37 (66.1%) 88 (64.7%)
  ≥ 70 19 (33.9%) 48 (35.3%)
Sex 0.817
 Male 34 (60.7%) 85 (62.5%)
 Female 22 (39.3%) 51 (37.5%)
BMI 0.002
  < 25 29 (51.8%) 102 (75.0%) 0.307 0.148–0.636 0.001
  ≥ 25 27 (48.2%) 34 (25.0%)
Cancer location 0.044
 Left-sided colon 49 (87.5%) 101 (74.3%) 2.021 0.764–5.347 0.157
 Right-sided colon 7 (12.5%) 35 (25.7%)
T stage 0.260
 T1–T2 33 (58.9%) 68 (50.0%)
 T3–T4 23 (41.1%) 68 (50.0%)
N stage 0.847
 N0 40 (71.4%) 99 (72.8%)
 N1–2 16 (28.6%) 37 (27.2%)
Obstruction 0.839
 Negative 46 (82.1%) 110 (80.9%)
 Positive 10 (17.9%) 26 (19.1%)
CEA level (ng/ml) 0.750
  < 5.0 46 (82.1%) 109 (80.1%)
  ≥ 5.0 10 (17.9%) 27 (19.9%)
Albumin level (g/dl) 0.673
  ≥ 3.5 55 (98.2%) 131 (96.3%)
  < 3.5 1 (1.8%) 5 (3.7%)
ICG tattooing dosage (mg) 0.002
  ≥ 1.0 7 (12.5%) 6 (4.4%) 1.579 0.273–69.124 0.610
 0.5–1.0 12 (21.4%) 63 (46.3%) 1
  < 0.5 37 (66.1%) 67 (49.3%) 0.350 0.155–0.793 0.012
Tattooing injection site  < 0.001
 Single 16 (28.6%) 10 (7.4%) 4.068 0.899–18.403 0.068
 Multiple (≥ 2 sites) 40 (71.4%) 126 (92.6%)
Camera light source  < 0.001
 Xenon 24 (42.9%) 20 (14.7%) 2.856 1.056–7.723 0.039
 Laser 32 (57.1%) 116 (85.3%)

FLNM fluorescence lymph node mapping, BMI body mass index, CEA carcinoembryonic antigen, OR odd ratio, CI Confidence interval, ICG Indocyanine green