Table 1.

Clinical and pathological features of the patient and specimen studied.

Patient ID	Block ID	Age at Index	Size (cm)	Laterality	Grade	Architecture	ER	HER2a	N. of Regions	Diagnosis Orderb
MCL76_044	12800	56	0.9	Left	Low	Cribriform	+	-	1	Index
MCL76_049	18100	50	6	Left	Low	Cribriform	+	-	1	Index
MCL76_060	16100	47	17	Left	Low	Cribriform	+	-	3	Index
MCL76_061	16200	34	8	Left	Low	Cribriform	+	-	4	Index
MCL76_064	15200	78	0.4	Left	Low	Cribriform	+	-	3	Recur. (+18 mos.)
MCL76_066	14400	70	1.1	Right	Low	Cribriform	+	-	3	Index
	16500	70	0.3	Right	Low	ADH	+	-	1	Recur. (+14 mos.)
MCL76_076	15700	45	4.1	Right	Low	Cribriform	+	-	5	Index
MCL76_078	15500	68	1.4	Left	Low	Solid	+	-	3	Index
MCL76_080	15800	59	3.7	Left	Low	ADH	+	-	3	Index
MCL78_020	10001	59	0.3	Right	Low	Cribriform	+	+	1	Index
MCL76_012	11600	50	3.6	Right	Inter.	Solid	+	-	2	Index
MCL76_048	13100	51	3.8	Right	Inter.	Cribriform	+	-	3	Index
MCL76_064	14600	78	NA	Left	Inter.	Solid	+	NA	1	Index
MCL76_067	16600	54	6	Left	Inter.	Solid	+	+	3	Index
MCL76_070	16400	69	8	Right	Inter.	Solid	+	-	3	Index
MCL76_071	14800	68	5.8	Right	Inter.	Micropapillary	-	-	3	Index
MCL76_074	14700	45	14	Right	Inter.	Cribriform	+	-	3	Index
MCL76_077	15300	70	1.2	Left	Inter.	Cribriform	-	+	2	Index
MCL76_079	15400	62	3.4	Right	Inter.	Cribriform	-	+	3	Index
MCL78_001	10001	50	2.5	Right	Inter.	Cribriform	NA	-	1	Index
MCL78_002	10001	48	2	Left	Inter.	Solid	+	-	1	Index
MCL78_006	10001	75	4	Left	Inter.	Cribriform	+	+	1	Index
MCL78_007	10001	43	1.6	Right	Inter.	Cribriform	+	+	1	Index
MCL78_008	10001	66	1.5	Right	Inter.	Solid	+	+	1	Index
MCL78_009	10001	78	2.4	Right	Inter.	Solid	+	-	1	Index
MCL78_010	10001	67	1.1	Left	Inter.	Cribriform	-	+	1	Index
MCL78_011	10001	59	0.6	Right	Inter.	Solid	+	+	1	Index
MCL78_013	10001	63	2.2	Right	Inter.	Mixed	-	+	1	Index
MCL78_016	10001	65	4.5	Left	Inter.	Solid	-	+	1	Index
MCL78_017	10001	52	2.5	Left	Inter.	Solid	+	+	1	Index
MCL78_018	10001	65	2	Right	Inter.	Mixed	+	equ	2	Index
MCL76_007	11000	78	3.5	Left	High	Solid	-	-	3	Index
	11100	78	2.6	Right	High	Solid	-	-	4	Recur. (+39 mos.)
MCL76_016	11800	35	5	Left	High	Mixed	+	+	4	Index
MCL76_025	16800	75	1.2	Right	High	Solid	-	NA	2	Index
MCL76_068	14900	59	9.5	Left	High	Cribriform	-	+	3	Index
MCL78_003	10001	43	5	Left	High	Solid	+	equ	1	Index
MCL78_005	10001	81	0.5	Right	High	Solid	+	-	1	Index
MCL78_012	10001	54	4	Right	High	Solid	-	+	1	Index
	10014	54	3	Right	High	Solid	-	NA	1	Synchronous
MCL78_015	10001	57	0.5	Left	High	Micropapillary	+	+	1	Index
MCL78_019	10001	57	1.9	Left	High	Solid	-	equ	1	Index

^aInferred from ERBB2 copy number and expression (Fig. S1), equ equivocal.

^bRecur. Recurrence, mos. months. All recurrence DCIS were in different quadrants than the index.