Table 2.
Description of all patient data available for study.
| Characteristics | Studies | Overall | ||||
|---|---|---|---|---|---|---|
| TUH | Bodilsen 20167 | Køster-Rasmussen 20086 | Stockdale 20118 | Miner (unpublished data) | ||
| Number· of patients | 25 | 358 | 132 | 39 | 106 | 659 |
| Male to female | 16:09 | 179:179 | 58:74 | 21:17 | NA | 274:279 |
| Age, years (mean ± SD) | 36.2 ± 22.0 | 56.7 ± 18.4 | 57.1 ± 19.5 | 44.4 ± 20.7 | 26.3 ± 28.0 | 50.8 ± 23.5 |
| Time to antibiotics, hours (mean ± SD) | 0.9 ± 2.0 | 9.9 ± 19.8 | 9.6 ± 34.5‡ | 2.6 ± 3.7 | 5.1 ± 9.1 | 8.3 ± 21.7 |
| Case fatality rate (%) | 8 | 23.5 | 30.3 | 18.4 | 8.5 | 21.6 |
| Neurological deficit (%) | 10.5 | 29.9 | 58.6 | NR | 20.8 | 32.4 |
| Infecting bacteria (n, %) | ||||||
| S. pneumoniae | 7 (28) | 194 (54.3) | 77 (58.8) | 17 (45) | NR | 295 (54.3) |
| N. meningitidis | 13 (52) | 58 (16.2) | 10 (13.7) | 20 (53) | NR | 101 (15.7) |
| S. aureus | 0 | 21 (5.9) | 6 (4.6) | 0 | NR | 27 (4.2) |
| H. influenzae | 2 (8) | 16 (4.5) | 2 (1.5) | 0 | NR | 20 (3.7) |
| Othersa | 2 (8) | 52 (14.6) | 22 (16.8) | 1 (2) | NR | 77 (14.2) |
| Other Gram negativeb | 1 (4) | 17 (4.7) | 6 (4.5) | 0 | NR | 24 (3.7) |
aIncludes Streptococcus spp·, E. faecalis, L. monocytogenes.
bIncludes E. coli, K. pneumoniae, P. multocida, Capnocytophaga spp.
TUH The Townsville University Hospital, SD standard deviation, N number, NR not reported.