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. 2022 Jan 13;12:688. doi: 10.1038/s41598-021-03837-0

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of non-viable B. burgdorferi on inflammatory mediator production from the DRG. Rhesus DRG tissues were exposed to live or sonicated B. burgdorferi for 4 h. Supernatants were analyzed for CCL2, CXCL-8 and IL-6. Results from tissues obtained from 3 animals is shown. ***p < 0.001; **p < 0.01; *p < 0.05. Significantly increased levels over medium control is denoted by the red asterisks. Black asterisks represent significantly lower levels compared to medium control. Bars represent standard deviation.