Transplanted NS/PCs promote functional recovery after SCI
(A) BMS scores before and after SCI in non-transplanted animals (PBS) and transplanted animals (mCherry-TP and hM4Di-TP) (PBS group, n = 20; mCherry-TP group, n = 18; hM4Di-TP group, n = 20).
(B) Comparison of paw angles determined by treadmill gait analysis performed at 9 weeks after transplantation (PBS group, n = 20; mCherry-TP group, n = 18; hM4Di-TP group, n = 20).
(C) Comparison of stride lengths determined by treadmill gait analysis performed at 9 weeks after transplantation (PBS group, n = 20; mCherry-TP group, n = 18; hM4Di-TP group, n = 20). ∗p < 0.05, ∗∗p < 0.01, and N.S., not significant according to the repeated-measures two-way ANOVA (A) and the Mann-Whitney U test following Kruskal-Wallis test (B and C). †p < 0.05, hM4Di-TP versus PBS, and $p < 0.05, mCherry-TP versus PBS, according to the two-sided unpaired Student t test. The data are presented as the mean ± SEM. All multiple testing data analyses were followed by Bonferroni correction.