Table 1.
Demographic and clinical characteristics of participants.
| Characteristics | MSa | Non-MS (n=24) | |||
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|
CIb (n=24) | Non-CI (n=29) |
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||
|
|
Age (years), mean (SE) | 50.87 (2.51) | 52.68 (2.35) | 46.04 (3.72) | |
|
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Sex (female), n (%) | 17 (70) | 23 (79) | 12 (50) | |
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|
Education (years), mean (SE) | 16.50 (0.47) | 16.79 (0.51) | 16.16 (0.41) | |
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Right-handedness, n (%) | 22 (91) | 23 (80) | 50 (100) | |
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Part- or full-time employed, n (%) | 11 (45%) | 15 (51%) | 17 (70%) | |
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SDMTc score, mean (SE) | 34.79 (1.34) | 49.34 (1.12)d | 51.20 (2.65)e | |
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SDMT z score, mean (SE) | –1.58 (0.08) | –0.05 (0.10)d | 0.26 (0.20)e | |
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Expanded Disability Status Scale (EDSS), median (IQR) | 4 (1.75) | 3 (1.5) | N/Af | |
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Disease duration (years), mean (SE) | 11.95 (1.83) | 13.71 (1.49) | N/A | |
| Race, n (%) | |||||
|
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White | 22 (92%) | 22 (76%) | 19 (79%) | |
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Black/African American | N/A | 2 (7%) | 1 (4%) | |
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Other/unknown | 2 (8%) | 5 (17%) | 4 (17%) | |
| MS subtype, n (%) | |||||
|
|
Relapsing-remitting | 18 (75%) | 23 (79%) | N/A | |
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Primary progressive | 2 (8%) | 2 (7%) | N/A | |
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Secondary progressive | 3 (13%) | 3 (10%) | N/A | |
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Clinically isolated syndrome (CIS) | N/A | 1 (3%) | N/A | |
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|
Unknown | 1 (4%) | N/A | N/A | |
aMS: multiple sclerosis.
bCI: cognitive impairment.
cSDMT: Symbol Digit Modalities Test.
dP<.001 for the comparison between CI and non-CI groups.
eP<.001 for the comparison between CI and non-MS groups.
fN/A: not applicable.