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. 2022 Jan 13;8(3):374–382. doi: 10.1001/jamaoncol.2021.6720

Table 2. Description of Current or Former Smokers Who Were White or African American Controls in the Inflammation, Health, Ancestry, and Lung Epidemiology Study.

Characteristic Controls, No. (%) P value
White (n = 838 [58%]) African American (n = 619 [43%])
Age, y
<50 101 (12) 82 (13) .04
50-59 267 (32) 226 (37)
60-69 307 (37) 226 (37)
70-79 144 (17) 73 (12)
≥80 19 (2) 12 (2)
Mean (SD) 61.1 (9.7) 59.5 (9.3) .002
Sex
Male 398 (48) 264 (43) .08
Female 440 (53) 355 (57)
BMI
<18.5 4 (1) 3 (1) .13
18.5-24.9 219 (26) 156 (25)
25.0-29.9 297 (35) 189 (31)
≥30.0 318 (38) 271 (44)
Mean (SD) 28.8 (5.8) 29.9 (6.9) .002
Smoking pack-years
≥30 470 (56) 232 (38) <.001
20-29 146 (17) 128 (21)
10-19 122 (15) 136 (22)
<10 100 (12) 123 (20)
Mean (SD) 36.4 (25.9) 26.6 (20.3) <.001
Smoking status
Former 467 (56) 196 (32) <.001
Current 371 (44) 423 (68)
Quit time, y (former smokers)
<15 229 (49) 116 (59) .02
≥15 238 (51) 80 (41)
Mean (SD) 16.9 (13.3) 13.7 (11.9) .002
Comorbidities
Cardiovascular diseasea 137 (16) 84 (14) .14
COPD 196 (23) 120 (19) .07
Diabetes 121 (14) 128 (21) .002
Hypertension 346 (41) 380 (61) <.001
Personal history of cancer
No 694 (83) 560 (91) <.001
Yes 144 (17) 59 (10)
Family history of cancer
No 693 (83) 525 (85) .31
Yes 145 (17) 94 (15)
Educational level
High school or less 240 (29) 282 (46) <.001
Greater than high school 598 (71) 337 (54)
PLCOm2012 risk score, mean (SD) 0.03 (0.05) 0.03 (0.07) .87

Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); COPD, chronic obstructive pulmonary disease; PLCOm2012, 2012 modification of the model from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.

a

Cardiovascular disease: stroke, arrhythmia, and congestive heart failure.