Weber 1999.
Methods | Randomised, double‐blind, placebo‐ controlled trial. Generation of allocation sequence: computer programme. Double blind: study personnel and subjects. Withdrawal/dropouts: numbers and reasons reported. Intention to treat analyses: yes. | |
Participants | Study country: Switzerland. Setting: HIV outpatient clinic. 68 HIV‐infected adults with reduced CD4 cell counts (34 in herb group and 34 in placebo group). HIV diagnosis criteria not described. | |
Interventions | Experiment:
Chinese herbs (35 different herbs), seven pills oral, four times daily, for six months. Control: Placebo, the same regimen as above. All participants continued their previous treatment during the trial. |
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Outcomes | CD4 and CD8 cell counts, viral loads, quality of life, adverse events, and safety (hematologic tests and chemistry variables). | |
Notes | 24 in herb group and 29 in placebo group finished the study. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Low risk | A ‐ Adequate |