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. 2005 Jul 20;2005(3):CD003937. doi: 10.1002/14651858.CD003937.pub2

Weber 1999.

Methods Randomised, double‐blind, placebo‐ controlled trial. 
 Generation of allocation sequence: computer programme. 
 Double blind: study personnel and subjects. 
 Withdrawal/dropouts: numbers and reasons reported. 
 Intention to treat analyses: yes.
Participants Study country: Switzerland. 
 Setting: HIV outpatient clinic. 
 68 HIV‐infected adults with reduced CD4 cell counts (34 in herb group and 34 in placebo group). 
 HIV diagnosis criteria not described.
Interventions Experiment: 
 Chinese herbs (35 different herbs), seven pills oral, four times daily, for six months.
Control: 
 Placebo, the same regimen as above.
All participants continued their previous treatment during the trial.
Outcomes CD4 and CD8 cell counts, viral loads, quality of life, adverse events, and safety (hematologic tests and chemistry variables).
Notes 24 in herb group and 29 in placebo group finished the study.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Low risk A ‐ Adequate