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. 2021 Dec 1;122(1):565–788. doi: 10.1021/acs.chemrev.1c00449

Scheme 151. Synthesis of Di- and Tetracyanopyrazines.

Scheme 151

Reagents and conditions: (a)291 2,3-diaminomaleonitrile, EtOH/AcOH (1:1), 80 °C, 11–16 h; (b) 4,5-diaminophthalonitrile, EtOH/AcOH (1:1), 80 °C, 11–16 h.