Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Dec 1;122(1):565–788. doi: 10.1021/acs.chemrev.1c00449

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 The Authors. Published by American Chemical Society

Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Scheme 237 — Reagents and conditions: (a)⁴³⁹ Br₂, Fe, nitrobenzene, 80 °C, 2 days; (b) RSNa, dry 1,3-dimethyl-2-imidazolidinone, rt, 8 h; (c)⁴⁴⁰ BBr₃, DCM, 0 °C to rt, then H₂O; (d) R′Br, K₂CO₃, DMF, 75 °C.