Scheme 293. Total Synthesis of Radermachol.
Reagents and conditions: (a)557 1,3-indanedione, CsF, MeCN, 75–80 °C, 1.5 h; (b) 3-methylcrotonoyl chloride, AlCl3, 55 °C, 2 h; (c) Me3SiI, CDCl3, 25 °C, 27 h; (d) TsOH, benzene, reflux, 5 h.
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