Skip to main content
. 2021 Dec 1;122(1):565–788. doi: 10.1021/acs.chemrev.1c00449

Scheme 357. Synthesis of Quadruply Ring-Fused Porphyrinsa.

Scheme 357

Reagents and conditions: (a)673 TFA, CHCl3; (b)674 NBS (5 equiv), CHCl3; (c)675 NBS (1.9 equiv), CHCl3; (d)674 (1) phenylboronic acid, Pd(PPh3)4, K2CO3, (2) TFA, NaHCO3, (3) Zn(OAc)2·2H2O; (e)675 2,4,6-trimethylphenylboronic acid, Pd(PPh3)4, K2CO3; (f)675 TFA, CHCl3.