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. 2021 Dec 1;122(1):565–788. doi: 10.1021/acs.chemrev.1c00449

Scheme 372. Synthesis of 28-Hetero-2,7-naphthiporphyrins.

Scheme 372

Reagents and conditions: (a)721 (1) phenylmagnesium bromide, THF, (2) H3O+; (b) (1) pyrrole, BF3·OEt2, CHCl3, N2, reflux, 48 h, (2) triethylamine; (c) (1) BF3·OEt2, CHCl3, (2) DDQ, 15 min; (d) Zn(Hg), toluene, N2; (e) O2; (f) PCl3, TEA, toluene, reflux, 80 min.