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. 2021 Dec 1;122(1):565–788. doi: 10.1021/acs.chemrev.1c00449

Scheme 68. Preparation of N-Annulated PDI Conjugates via Cross-Coupling Reactions.

Scheme 68

Reagents and conditions: (a)124 B2pin2, Pd(dppf)Cl2, NaOAc, 10:3/1 DMF/toluene/H2O, 70 °C, overnight, 49%; (b) Pd(PPh3)4, toluene, 100 °C, 24 h, 72%; (c) Pd(PPh3)4, K2CO3, 2:1 toluene/H2O, reflux, 2 days, 41%.