Figure 2.

Treatment effects by APACHE-II score. Odds ratio for mortality <1 indicates treatment effect favors Pes-guided PEEP. Incidence rate ratio >1 indicates treatment effect favors Pes-guided PEEP. Effect estimates are reported from the overall study population or unadjusted subgroup logistic or Poisson models as indicated. *P value for interaction term. APACHE-II = Acute Physiology and Chronic Health Evaluation II; IQR = interquartile range; PEEP = positive end-expiratory pressure; Pes = esophageal pressure.