Table 3.
Effects of antihypertensive treatment on cognitive performance on MMSE and MoCA
| Variable | Antihypertensive treatment (n = 314) | Control (n = 324) | OR (95%CI) | P value | Adjusted ORa (95% CI) | P value |
|---|---|---|---|---|---|---|
| MMSE score, median (IQR) | 26 (22–29) | 26 (22–29) | 0.50 | |||
| MMSE <24, n (%) | 96 (30.9) | 96 (29.7) | 1.06 (0.75–1.48) | 0.75 | 1.09 (0.76–1.56) | 0.64 |
| MMSE category, n (%) | ||||||
| 24–30 | 215 (69.1) | 227 (70.3) | 1.05 (0.75–1.46) | 0.80 | 1.07 (0.75–1.51) | 0.71 |
| 18–23 | 63 (20.3) | 61 (18.9) | ||||
| 0–17 | 33 (10.6) | 35 (10.8) | ||||
| MoCA score, median (IQR) | 22 (18–26) | 22 (18–26) | 0.57 | |||
| MoCA <26, n (%) | 218 (70.6) | 227 (70.7) | 0.99 (0.70–1.40) | 0.96 | 0.97 (0.68–1.38) | 0.85 |
Data are presented as median (interquartile range) and number (percentages). MMSE < 24 or MoCA < 26 indicate cognitive impairment.
a
Adjusted for age, sex, education levels, and NIHSS score at baseline.
MMSE: Mini Mental State Examination; MoCA: Montreal Cognitive Assessment.