Comparison 6. CFOs versus PFOs in JIA.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
6.1 Pain	2	87	Mean Difference (IV, Random, 95% CI)	‐1.48 [‐3.23, 0.26]
6.2 Function	1		Mean Difference (IV, Random, 95% CI)	Subtotals only
6.2.1 FFi ‐ disability	1	27	Mean Difference (IV, Random, 95% CI)	‐14.38 [‐30.22, 1.46]
6.2.2 FFI ‐ activity limitation	1	27	Mean Difference (IV, Random, 95% CI)	‐11.42 [‐23.91, 1.07]
6.2.3 FFI ‐ foot pain	1	27	Mean Difference (IV, Random, 95% CI)	‐12.11 [‐28.95, 4.73]
6.3 Quality of life	2		Mean Difference (IV, Random, 95% CI)	Subtotals only
6.3.1 PedsQL ‐ child‐rated	2	83	Mean Difference (IV, Random, 95% CI)	8.64 [‐3.90, 21.18]
6.3.2 PedsQL ‐ parent‐rated	2	84	Mean Difference (IV, Random, 95% CI)	2.94 [‐11.00, 16.88]
6.4 Treatment success (timed walking)	1	27	Mean Difference (IV, Random, 95% CI)	‐0.95 [‐1.88, ‐0.02]
6.5 Withdrawal due to adverse events	2	87	Risk Ratio (M‐H, Random, 95% CI)	0.80 [0.13, 4.87]