Table 1.
Timing of vaccination and specimen collection in the ESCUDDO study.
| Procedure | Study Visit | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||||||
| M0 (yr-0) | M1* | M6 | M7* | M12 (yr-1) | M18 (yr-1.5) | M24 (yr-2) | M30 (yr-2.5) | M36 (yr-3) | M42 (yr-3.5) | M48 (yr-4) | M54 (yr-4.5) | M60 (yr-5) | |
|
| |||||||||||||
| Trial EHS | Trial | Trial EHS | Trial | Trial | Trial | Trial | Trial | Trial | Trial | Trial | Trial EOSS | Trial EOSS | |
|
| |||||||||||||
| Vaccination | • | • | • | • | |||||||||
|
| |||||||||||||
| Specimen collections for all participants | |||||||||||||
| Urine for HPV test | • | • | • | • | • | • | • | • | • | • | • | • | |
| 10 mL blood for serum | • | • | • | • | • | • | • | • | • | • | |||
| Self-collected cervicovaginal sample (15+ years only) | • | • | • | • | • | • | • | • | • | • | • | ||
|
| |||||||||||||
| Additional samples collected from ISG | |||||||||||||
| Urine for other tests | • | • | • | ||||||||||
| Spit | • | • | • | • | • | • | • | ||||||
| 10 mL blood for serum | • | • | • | • | • | • | • | • | |||||
| Blood for PBMC isolation | • | • | • | • | • | • | • | • | |||||
M, Month; yr; year; EHS, Epidemiologic HPV Survey; EOSS, End-of-Study Survey; ISG, Immunogenicity Subgroup; PBMC, Peripheral Blood Mononuclear Cells.
*
Visits conducted only among ISG participants.