Table 4.
Cognitive, language and motor composite scale scores during the first 24 months of age associated with 1 μg/m3 increase in the mean PM2.5 prenatal levela
Scale | Ageb | PM2.5 window of exposure | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1st trimester |
2nd trimester |
3rd trimester |
All pregnancy |
||||||||||
β | p | 95% CI | β | p | 95% CI | β | p | 95% CI | β | p | 95% CI | ||
Cognitive | −0.26 | 0.04 | −0.51, −0.02 | −0.50 | 0.00 | −0.75, −0.25 | −0.21 | 0.04 | −0.42, −0.01 | −0.93 | 0.00 | −1.27, −0.58 | |
Language | 6 | −0.31 | 0.02 | −0.56, −0.06 | −0.39 | 0.00 | −0.65, −0.13 | −0.30 | 0.01 | −0.52, −0.09 | −0.95 | 0.00 | −1.29, −0.60 |
Motor | −0.13 | 0.31 | −0.37, 0.12 | −0.11 | 0.40 | −0.36, 0.14 | 0.10 | 0.33 | −0.10, 0.31 | −0.14 | 0.42 | −0.49, 0.20 | |
| |||||||||||||
Cognitive | 0.05 | 0.70 | −0.19. 0.28 | 0.03 | 0.80 | −0.21, 0.27 | −0.26 | 0.01 | −0.45, −0.07 | −0.14 | 0.35 | −0.43, 0.15 | |
Language | 12 | −0.18 | 0.14 | −0.41. 0.06 | −0.05 | 0.69 | −0.29, 0.19 | −0.27 | 0.01 | −0.47, −0.08 | −0.58 | 0.00 | −0.88, −0.28 |
Motor | 0.07 | 0.55 | −0.16, 0.30 | 0.14 | 0.26 | −0.10, 0.38 | −0.17 | 0.09 | −0.36, 0.02 | −0.01 | 0.93 | −0.31, 0.28 | |
| |||||||||||||
Cognitive | 0.17 | 0.16 | −0.07, 0.41 | −0.02 | 0.86 | −0.27, 0.23 | −0.20 | 0.04 | −0.39, −0.01 | −0.13 | 0.40 | −0.44, 0.18 | |
Language | 18 | 0.00 | 0.99 | −0.25, 0.24 | 0.01 | 0.96 | −0.25, 0.26 | −0.08 | 0.43 | −0.27, 0.12 | −0.08 | 0.63 | −0.38, 0.23 |
Motor | 0.14 | 0.26 | −0.11, 0.39 | 0.08 | 0.52 | −0.17, 0.34 | −0.04 | 0.71 | −0.23, 0.16 | 0.13 | 0.41 | −0.18, 0.44 | |
| |||||||||||||
Cognitive | 0.26 | 0.05 | 0.00, 0.51 | 0.14 | 0.34 | −0.14, 0.42 | −0.14 | 0.20 | −0.35, 0.07 | 0.07 | 0.73 | −0.31, 0.45 | |
Language | 24 | −0.11 | 0.41 | −0.36, 0.15 | −0.12 | 0.40 | −0.40, 0.16 | −0.12 | 0.28 | −0.33, 0.09 | −0.38 | 0.05 | −0.77, −0.01 |
Motor | 0.24 | 0.07 | −0.02, 0.50 | 0.13 | 0.35 | −0.15, 0.41 | −0.02 | 0.88 | −0.23, 0.20 | 0.19 | 0.33 | −0.19, 0.57 |
95% CI: 95% confidence interval; P: p value
The number of mother–child pairs included in the analysis n=445
Models adjusted by child’s sex, gestational age, birthweight, prenatal smoking and maternal IQ.
Age at evaluation in months