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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: Int J Hyg Environ Health. 2021 Feb 11;233:113695. doi: 10.1016/j.ijheh.2021.113695

Table 4.

Cognitive, language and motor composite scale scores during the first 24 months of age associated with 1 μg/m3 increase in the mean PM2.5 prenatal levela

Scale Ageb PM2.5 window of exposure
1st trimester
2nd trimester
3rd trimester
All pregnancy
β p 95% CI β p 95% CI β p 95% CI β p 95% CI
Cognitive −0.26 0.04 −0.51, −0.02 −0.50 0.00 −0.75, −0.25 −0.21 0.04 −0.42, −0.01 −0.93 0.00 −1.27, −0.58
Language  6 −0.31 0.02 −0.56, −0.06 −0.39 0.00 −0.65, −0.13 −0.30 0.01 −0.52, −0.09 −0.95 0.00 −1.29, −0.60
Motor −0.13 0.31 −0.37, 0.12 −0.11 0.40 −0.36, 0.14 0.10 0.33 −0.10, 0.31 −0.14 0.42 −0.49, 0.20

Cognitive 0.05 0.70 −0.19. 0.28 0.03 0.80 −0.21, 0.27 −0.26 0.01 −0.45, −0.07 −0.14 0.35 −0.43, 0.15
Language  12 −0.18 0.14 −0.41. 0.06 −0.05 0.69 −0.29, 0.19 −0.27 0.01 −0.47, −0.08 −0.58 0.00 −0.88, −0.28
Motor 0.07 0.55 −0.16, 0.30 0.14 0.26 −0.10, 0.38 −0.17 0.09 −0.36, 0.02 −0.01 0.93 −0.31, 0.28

Cognitive 0.17 0.16 −0.07, 0.41 −0.02 0.86 −0.27, 0.23 −0.20 0.04 −0.39, −0.01 −0.13 0.40 −0.44, 0.18
Language  18 0.00 0.99 −0.25, 0.24 0.01 0.96 −0.25, 0.26 −0.08 0.43 −0.27, 0.12 −0.08 0.63 −0.38, 0.23
Motor 0.14 0.26 −0.11, 0.39 0.08 0.52 −0.17, 0.34 −0.04 0.71 −0.23, 0.16 0.13 0.41 −0.18, 0.44

Cognitive 0.26 0.05 0.00, 0.51 0.14 0.34 −0.14, 0.42 −0.14 0.20 −0.35, 0.07 0.07 0.73 −0.31, 0.45
Language  24 −0.11 0.41 −0.36, 0.15 −0.12 0.40 −0.40, 0.16 −0.12 0.28 −0.33, 0.09 −0.38 0.05 −0.77, −0.01
Motor 0.24 0.07 −0.02, 0.50 0.13 0.35 −0.15, 0.41 −0.02 0.88 −0.23, 0.20 0.19 0.33 −0.19, 0.57

95% CI: 95% confidence interval; P: p value

The number of mother–child pairs included in the analysis n=445

a

Models adjusted by child’s sex, gestational age, birthweight, prenatal smoking and maternal IQ.

b

Age at evaluation in months