TABLE 3.
Causes of graft failure by time after kidney transplantation
| Cause | Time after kidney transplantation | |||
|---|---|---|---|---|
| Total | <1 y | 1–5 y | >5 y | |
| Total | 553 (100%) | 131 (23.7%) | 235 (42.5%) | 188 (33.8%) |
| Alloimmune | 214 (38.7%) | 16 (12.2%) | 117 (49.8%) | 81 (43.3%) |
| Glomerular diseases | 103 (18.6%) | 18 (13.7%) | 41 (17.4%) | 44 (23.5%) |
| Renal tubular injuries | 77 (13.9%) | 12 (9.2%) | 41 (17.4%) | 24 (12.8%) |
| Primary dysfunction/surgical | 79 (14.3%) | 79 (60.3%) | 0 (0.0%) | 0 (0.0%) |
| BK nephropathy | 24 (4.3%) | 4 (3.1%) | 10 (4.3%) | 10 (5.3%) |
| Unknown/Other | 56 (10.1%) | 2 (1.5%) | 26 (11.1%) | 28 (15.0%) |
| Number at risk at the beginning of the time period | 5752 | 5752 | 5396 | 3716 |
Graft failure (not due to death) by category was determined by an adjudication process in which 2 or more expert nephrologists determined the cause based on chart review. The table also shows the causes of graft loss with respect to time after kidney transplantation and the number of patients followed at the beginning of the time period.
BK, polyoma virus.