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. 2022 Jan 14;17(1):e0261958. doi: 10.1371/journal.pone.0261958

Table 2. Subsidiary test results, clinical characteristics, and outcomes of the patients included in the study (N = 375).

Hospital admission exams Normal range
    Hemoglobin (g/dl) 12.0–16.0 13.0 ± 2.1
    Total leukocytes (n/mm3) 4,000–8,000 8,117 (5,500–11,200)
    Total lymphocytes (n/mm3) 1,000–3,900 974 (699–1489)
    Platelets (n/mm3) 150,000–400,000 179,000 (141,000–231,750)
    Serum creatinine (mg/dl) 0.6–1.3 1.16 (0.90–1.78)
    D-dimer (ng/ml) < 0.5 1.5 (0.7–9.1)
    C-reactive protein (mg/dl) < 0.1 15.5 (7.6–25.1)
Pulmonary involvement on tomography
    Mild, % (n) 13.1 (49)
    Moderate, % (n) 32.0 (120)
    Severe, % (n) 39.7 (149)
    Unknown, % (n) 15.2 (57)
Severity score at ICU admission
    SAPS 3 54 (46–66)
    Unknown, % (n) 42.9 (161)
Mechanical ventilation, % (n) 88.5 (332)
Organ dysfunctions during hospitalization
    Circulatory, % (n) 85.3 (320)
    Pulmonary, % (n) 78.7 (295)
    Coagulopathy, % (n) 30.4 (114)
    Hepatic
        Yes, % (n) 13.3 (50)
        No, % (n) 73.3 (275)
        Unknown, % (n) 13.3 (50)
    Kidney, % (n) 100.0 (375)
Medications
    Azithromycin + hydroxychloroquine, % (n) 37.6 (141)
    Other antibiotics, not azithromycin
        Yes, % (n) 85.9 (322)
        No, % (n) 2.7 (10)
        Unknown, % (n) 11.5 (43)
    Corticosteroids, % (n) 60.3 (226)
    Continuous heparin infusion
        Yes, % (n) 23.7 (89)
        No, % (n) 75.9 (286)
Laboratory exams at first RRT indication
    Creatinine (mg/dl) 0.6–1.3 4.05 (2.90–5.60)
    Urea (mg/dl) 16–40 152.8 (98.5–211.0)
    Potassium (mEq/l) 3.5–5.1 4.8 (4.2–5.5)
    Bicarbonate (mEq/l) 22–27 22.1 (19.0–25.9)
Exams during the RRT period
    Creatinine (mg/dl) 0.6–1.3 3.63 (2.12–5.10)
    Urea (mg/dl) 16–40 126.5 (88.0–174.1)
    Potassium (mEq/l) 3.5–5.1 4.7 (4.1–5.4)
    Bicarbonate (mEq/l) 22–27 23.0 (19.6–26.0)
RRT method
    Intermittent, % (n) 56.5 (212)
    SLED, % (n) 8.3 (31)
    Continuous, % (n) 18.7 (70)
    Combination of methods, % (n) 16.5 (62)
Time on RRT (days) 6 (2–15)
Outcomes
    Total length of stay (days) 19 (11–30)
    Death, % (n) 72.5 (272)
    Discharge without RRT, % (n) 77.7 (80/103)
    Discharge dependent on RRT, % (n) 22.3 (23/103)

Data are presented as the mean ± SD, the median and interquartile range (p25-p75), or a percentage. SLED, sustained low-efficiency dialysis.