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. 2022 Jan 13;14(1):1952838. doi: 10.1080/20002297.2021.1952838

Table 1.

Characteristic differences between VBNC, persistent and culturable states

VBNC Persistent Culturable
Not culturable on normal culture medium Still culturable Can grow on normal culture medium
Lowered metabolism Active metabolism Highest metabolism
High antibiotic tolerance Antibiotic tolerance Antibiotic sensitive
Highly tolerant to stress conditions Can tolerate stress moderately Do not tolerate stress conditions
Takes a longer time to grow after stress conditions are removed Quickly regain growth after stress conditions are removed Lose growth under stress conditions well
Changes in cellular morphology No changes in cellular morphology No change in cellular morphology