Figure 4. GO enrichment of DEGs.

Left panel: GO biological process (BP) terms of enrichment (q < 0.05) are listed; when no such BP or molecular function term existed, cellular compartment (CC) terms of enrichment (q < 0.05) are listed. Middle panel: –log₁₀ enrichment q value (purple bars) and proportion of DEGs in GO term over GO term genes (red bars). Right panel: top 25 DEGs that were mostly observed in the selected GO terms. DEGs were identified at q < 0.1 in both AD versus control and PSP versus control comparisons. Up, upregulated; down, downregulated; MSigDB, Molecular Signatures Database.