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. 2022 Jan 7;2022:2717291. doi: 10.1155/2022/2717291

Table 2.

Percentage of patients with trough BP < 140/85 mm Hg, BP < 130/80 mm Hg, and BP 198 < 140/90 mm Hg using GEE (logistic regression model): FAS and LOCF.

Trough BP Visit Switched (n = 289) Patients
Add-on (n = 90) Overall (N = 380)
<140/85 mm Hg Week 6
N 276 85 362
n (%) 178 (64.5) 54 (63.5) 233 (64.4)
Adjusted % 58.9 58.2 58.7
99% CI (48.99, 68.12) (41.22, 73.48) (49.53, 67.36)
95% CI (51.38, 66.01) (45.25, 70.16) (51.75, 65.37)
Week 12
N 276 85 362
n (%) 165 (59.8) 56 (65.9) 221 (61.0)
Adjusted % 53.4 61.0 54.8
99% CI (43.40, 63.08) (44.07, 75.70) (45.54, 63.78)
95% CI (45.76, 60.82) (48.15, 72.56) (47.75, 61.70)

<130/80 mm Hg Week 6
N 276 85 362
n (%) 83 (30.1) 28 (32.9) 111 (30.7)
Adjusted % 22.6 24.9 22.9
99% CI (14.46, 33.44) (13.09, 42.15) (14.93, 33.40)
95% CI (16.15, 30.61) (15.39, 37.64) (16.60, 30.67)
Week 12
N 276 85 362
n (%) 93 (33.7) 34 (40.0) 127 (35.1)
Adjusted % 25.9 31.8 27.0
99% CI (17.01, 37.26) (18.66, 48.66) (18.18, 37.99)
95% CI (18.88, 34.34) (21.37, 44.45) (20.06, 35.18)

<140/90 mm Hg Week 6
N 276 85 362
n (%) 186 (67.4) 56 (65.9) 243 (67.1)
Adjusted % 64.0 63.0 63.8
99% CI (54.59, 72.41) (45.37, 77.74) (55.12, 71.72)
95% CI (56.89, 70.51) (49.65, 74.63) (57.26, 69.93)
Week 12
N 276 85 362
n (%) 182 (65.9) 58 (68.2) 240 (66.3)
Adjusted % 62.2 65.9 62.8
99% CI (52.51, 71.04) (48.42, 79.92) (53.88, 70.96)
95% CI (54.88, 69.04) (52.74, 77.00) (56.06, 69.11)

CI, confidence interval; FAS, full analysis set; GEE, generalized estimated equation; LOCF, last observation carried forward. N' = number of patients with nonmissing values and used as denominator to calculate percentage. The GEE logistic regression model was adjusted for baseline SBP (systolic blood pressure), country, baseline hypertension treatment status, and visit. One patient from the treatment-naïve group was considered only in the overall analysis.