Table 2. Diagnostic test accuracies for endoscopic characterization with histopathology as reference standard.
| Endoscopic characterization | ||||
|
All polyps, % (95 % CI)
(N = 269) |
High confidence all polyps, % (95 % CI)
(N = 223) |
Diminutive polyps, % (95 % CI)
(N = 220) |
Diminutive polyps with high confidence, % (95 %CI)
(N = 178) |
|
| Overall accuracy 1 | 75.1 (69.4–80.1) | 78.0 (72.0–83.2) | 74.7 (68.4–80.3) | 78.2 (71.4–84.0) |
| Adenomas vs serrated polyps | ||||
|
82.5 (77.5–86.9) | 86.1 (80.9–90.3) | 81.9 (76.2–86.7) | 86.0 (80.1–90.8) |
|
80.0 (73.1–85.8) | 84.9 (77.8–90.4) | 79.0 (71.2–85.5) | 84.8 (76.8–90.9) |
|
86.5 (78.4–92.4) | 88.1 (79.2–94.1) | 86.8 (77.5–93.2) | 88.1 (77.8–94.7) |
|
90.4 (84.4–94.7) | 92.2 (86.1–96.2) | 90.8 (84.2–95.3) | 92.2 (95.3–96.6) |
|
73.2 (64.4–80.8) | 77.9 (68.2–85.8) | 71.3 (61.4–79.9) | 77.6 (66.6–86.4) |
| SSLs vs non-SSLs | ||||
|
88.5 (84.0–92.0) | 87.9 (82.9–91.9) | 91.0 (86.4–94.4) | 90.5 (85.2–94.4) |
|
44.4 (25.5–64.7) | 47.8 (26.8–69.4) | 21.4 (4.7–50.8) | 25.0 (5.5–57.2) |
|
93.3 (89.5–96.2) | 92.5 (87.9–95.7) | 95.6 (91.9–98.0) | 95.2 (90.8–97.9) |
|
42.9 (24.5–62.8) | 42.3 (23.3–63.1) | 25.0 (5.5–57.2) | 27.3 (6.0–61.0) |
|
93.8 (90.0–96.5) | 93.9 (89.6–96.8) | 94.7 (90.8–97.3) | 94.6 (90.0–97.5) |
| HPs vs non-HPs | ||||
|
79.2 (73.8–83.9) | 82.1 (76.4–86.9) | 76.5 (70.3–81.9) | 79.9 (73.3–85.5) |
|
75.3 (64.2–84.4) | 73.8 (60.9–84.2) | 76.8 (65.1–86.1) | 76.4 (63.0–86.8) |
|
80.7 (74.4–86.1) | 85.2 (78.8–90.3) | 76.3 (68.8–82.8) | 81.5 (73.5–87.9) |
|
61.1 (50.5–70.9) | 65.2 (52.8–76.3) | 59.6 (48.6–69.8) | 64.6 (51.8–76.1) |
|
89.1 (83.5–93.3) | 89.6 (83.7–93.9) | 87.9 (81.1–92.9) | 88.6 (81.3–93.8) |
PPV, positive predictive value; CI, confidence interval; NPV, negative predictive value; SSL, sessile serrated lesion; HP, hyperplastic polyp.
1
For the calculation of the overall accuracy adenomas, SSLs and HPs were considered different histological subtypes.