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. 2021 Dec 15;13(12):e20445. doi: 10.7759/cureus.20445

Table 2. Median volume that patients received within 24 hours.

Both groups are classified in injury (<0.5ml/kg/hr*12) or failure (<0.3ml/kg/hr*24) according to RIFLE criteria within 24 hours in the intensive care unit. 

* p-value (0.07); ** p-value (0.06);

Abbreviation: (FO%) - Fluid accumulation; IQR - Interquartile range; RIFLE - Risk, Injury, Failure, Loss, and End-stage

  Furosemide group Furosemide plus fenoldopam group
RIFLE-I or F (n=48) RIFLE-R (n=39) RIFLE-I or -F (n=20) RIFLE-R (n=19)
Creatinine serum 24 hrs. (mg/dL) Median (IQR 25th-75th) 1.22 (0.82-1.79) 1.37 (0.91-1.77) 1.33 (0.86-2.51) 1.06 (0.6-1.84)
Creatinine serum 48 hrs.(mg/dL) Median (IQR 25th-75th) 1.28 (0.86-1.98) 1.24 (0.79-1.84) 1.47 (0.83-2.94) 1.20 (0.59-1.81)
IV Fluids within 24 hrs (ml) Median (IQR 25th-75th) 4197 (2881-6313) 2598 (2032-4981) 3965 (2728-6263) 3320 (2685-4478)
Urine Output first 12 hrs (ml) Median (IQR 25th-75th) 205 (137-300) 782 (500-1725) 287 (170-483) 950 (535-1550)
Urine Output second 24 hrs (ml) Median (IQR 25th-75th) 320 (20-450) 865 (675-1205) 421 (163-545) 1025 (640-1325)
Creatinine clearance 24 hrs. (mg/dL) Median (IQR 25th-75th) 48.46 (30.4-82.1) 49 (29.6-98.7) 40.65 (20.6-73.30 66.50 (35.3-109.3)
Fluid balance 24 hrs (ml) Median (IQR 25th-75th) 3700 (146-5656) 1325 (675-2998) 3192 (1618-6565) 882 (372-3014)
Fluid Accumulate, FO% (ml) Median (IQR 25th-75th) 5179 (2121-7233)  1588 (774-3765) 4230 (2132-7843)* 1074 (612-3996)**