Table 1:
Summary of E69 Genotype, work site, and demographic variables by Diagnosis. Chi-square p-value for Race was calculated after merging Black and Other categories and dropping the Missing category. Chi-square p-value for Ethnicity was calculated after dropping the Missing category. Q1 = < 0.06 μg/m3; Q2 = 0.06 < 0.3 μg/m3; Q3 = >0.3 – 1.0 μg/m3; Q4 = >1 μg/m3
| Diagnosis N (%) | |||||||
|---|---|---|---|---|---|---|---|
| Control | BeS | BeS/CBD | CBD | Total | Chi-square p-value |
||
| E69 Alleles | 0 | 549 (77.3) | 93 (13.1) | 12 (1.7) | 56 (7.9) | 710 | 5.59 E-87 |
| 1 | 302 (32.3) | 291 (31.1) | 37 (4.0) | 305 (32.6) | 935 | ||
| 2 | 39 (19.4) | 60 (29.9) | 14 (7.0) | 88 (43.7) | 201 | ||
| Site | BBB | 100 (43.1) | 86 (37.1) | 19 (8.2) | 27 (11.6) | 232 | 4.45 E-28 |
| PENN | 287 (67.2) | 73 (17.1) | 0 | 67 (15.7) | 427 | ||
| NIOSH | 61 (38.9) | 39 (24.8) | 0 | 57 (36.3) | 157 | ||
| NJH | 442 (42.9) | 246 (23.9) | 44 (4.3) | 298 (28.9) | 1030 | ||
| Sex | Male | 784 (49.4) | 364 (23.0) | 52 (3.3) | 385 (24.3) | 1585 | 0.0211 |
| Female | 106 (40.6) | 80 (30.7) | 11 (4.2) | 64 (24.5) | 261 | ||
| Race | White | 885 (48.3) | 437 (23.9) | 61 (3.3) | 448 (24.5) | 1831 | 0.1437 |
| Black | 4 (44.4) | 4 (44.4) | 0 | 1 (11.1) | 9 | ||
| Other | 1 (25.0) | 2 (50.0) | 1 (25.0) | 0 | 4 | ||
| Missing | 0 | 1 (50.0) | 1 (50.0) | 0 | 2 | ||
| Ethnicity | Hispanic | 40 (40.8) | 21 (21.4) | 7 (7.1) | 30 (30.6) | 98 | 0.0567 |
| Non-Hispanic | 850 (48.7) | 421 (24.1) | 55 (3.2) | 419 (24.0) | 1745 | ||
| Missing | 0 | 2 (66.6) | 1 (33.3) | 0 | 3 | ||
| Lifetime Average Exposure Quartile | Q1 | 125 (30.0) | 177 (42.5) | 30 (7.2) | 84 (20.2) | 416 | 9.04 E-34 |
| Q2 | 197 (47.9) | 98 (23.8) | 18 (4.4) | 98 (23.8) | 411 | ||
| Q3 | 255 (56.4) | 76 (16.8) | 8 (1.8) | 113 (25.0) | 452 | ||
| Q4 | 247 (65.9) | 44 (11.7) | 4 (1.1) | 80 (21.3) | 375 | ||
| Total | 890 | 444 | 63 | 449 | 1846 | ||