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. Author manuscript; available in PMC: 2022 Jan 15.
Published in final edited form as: Curr Drug Metab. 2021;22(14):1114–1123. doi: 10.2174/1389200222666211202093841

Table 3.

Excretion of MIDD0301 and its metabolites after IP injection.

0-24 hours 24-48 hours 0-48 hours
Feces (%)1 Urine (%)1 Feces (%)1 Urine (%)1 Feces & Urine (%)1
MIDD0301 43.2 ± 5.9 0.3 ± 0.2 0.3 ± 0.1 0.1 ± 0.04 43.9 ± 6.24
MIDD0301 taurine 16.2 ± 0.9 0.4 ± 0.1 <LOD <LOD 16.6 ± 1.0
MIDD0301 glucoside <LOD 13.9 ± 7.1 <LOD 2.4 ± 0.2 16.3 ± 7.3
MIDD0301 glucuronide <LOD 2.8 ± 1.2 <LOD 0.3 ± 0.2 3.1 ± 1.4
Total 59.4 ± 6.8 17.4 ± 8.6 0.3 ± 0.1 2.8 ± 0.44 79.9 ± 15.94
1

% is based on moles of MIDD0301 administered; LOD, lower limit of detection; data is presented as average (n = 3) ± StD